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Senior Advisor, GCR Partnerships

Open Philanthropy

Open Philanthropy

Sales & Business Development
San Francisco, CA, USA
Posted on Mar 21, 2026

Location

San Francisco

Employment Type

Full time

Department

Partnerships

Coefficient Giving is hiring a Senior Advisor to build and deepen relationships with major donors in the San Francisco Bay Area who are interested in reducing global catastrophic risks. We believe the next few years represent a unique opportunity to significantly scale philanthropic funding for AI safety and biosecurity. The Senior Advisor will support a new generation of major donors early in their philanthropic journey, helping them move quickly toward concrete, high-impact giving.

The decisions made in AI and biosecurity over the next few years will matter enormously. Your job is to ensure more philanthropic capital reaches the highest-impact opportunities, faster than it would otherwise.

About Coefficient Giving

Coefficient Giving is a philanthropic funder and advisor. Since 2014, we’ve directed over $4 billion in grants as part of our mission to help others as much as we can with the resources available to us. We work with a range of donors who share our commitment to cost-effective, high-impact giving. Our current funds include Science and Global Health R&D, Navigating Transformative Artificial Intelligence, Abundance & Growth, Farm Animal Welfare, Biosecurity & Pandemic Preparedness, and more.

We’re proud of our track record:

  • Our grants to evidence-backed global health programs have saved over 100,000 lives, and our farm animal welfare grants have improved the lives of over 3 billion animals.

  • We supported the late-stage clinical trials for the R21 malaria vaccine, now being scaled to protect millions of kids globally.

  • We were the earliest major funder of the YIMBY movement to build more housing. Our grantees have led the charge on major wins like City of Yes in New York and SB 79 in California, which will enable hundreds of thousands of new housing units.

  • We jump-started the field of AI safety and security and have played a vital role in addressing other existential threats, such as mirror bacteria.

About the Partnerships team

The Partnerships function was launched in 2024, leveraging our internal research and grantmaking expertise to direct donors to the highest-impact funding opportunities available. In 2025, Partnerships helped direct more than $200 million to high-impact causes outside our core relationship with Good Ventures. We see the coming years as a unique opportunity to be even more ambitious in scaling this work.

The Partnerships team builds relationships with philanthropists who are interested in cost-effective giving across our cause areas. Within our Global Catastrophic Risks (GCR) portfolio, we find and match donors with promising but unfunded opportunities in AI safety and biosecurity. (This is strategic advisory work, not fundraising for Coefficient’s own vehicles.) The GCR Partnerships team currently works closely with more than two dozen donor partners to fill funding gaps at worthwhile projects and seed new organizations. We manage the entire pipeline, from building relationships with existing and potential donors to matching them with suitable opportunities and reporting back on the impact of their giving. Over time, we expect to significantly scale our work, advising on hundreds of millions of dollars in new GCR funding annually.

Our work blends donor relationship support, opportunity matching, grantee coordination, and system-building for a new, growing function. We are a small, nimble team that works fast and aspires to embody Coefficient Giving’s operating values: ownership, openness, calibration, and inclusiveness.

About the role

The San Francisco Bay Area is home to a growing cohort of donors who are ready to deploy significant philanthropic capital cost-effectively across many causes, including AI safety and biosecurity. We’re building the advisory infrastructure to meet that moment, and we expect the most important partnerships to require a higher level of staffing and support than we’ve provided to date.

We're looking for someone who can engage as a peer with major donors who have deep technical backgrounds in AI (alongside other ultra-high-net-worth philanthropists). We tend to work with people who are deeply informed about AI developments and care a lot about cost-effectiveness. We’re looking for a Senior Advisor who speaks that language.

The Senior Advisor would serve as a trusted advisor, translating donor interest into high-impact grants and building a durable network of philanthropists focused on reducing global catastrophic risks. They would co-own and help scale our engagement with major philanthropists, ensuring that more capital flows to high-impact GCR opportunities, particularly those that benefit from a diversified funding base.

Responsibilities:

  • Build the next generation of GCR philanthropists: Identify and cultivate emerging major donors early in their giving journey; develop programming and content strategies to move high-potential individuals toward substantial GCR-aligned commitments.

  • Serve as the senior GCR Partnerships presence in the Bay Area: Build and sustain peer-level relationships with major donors, foundation leaders, and senior figures across the tech industry and leading AI safety nonprofits; represent the team at dinners, convenings, and conferences; be a go-to thought partner for philanthropists navigating GCR giving.

  • Shape and activate funding opportunities: Craft compelling cases for time-sensitive or strategically important opportunities; advise donors on portfolio construction, timing, and where their capital can be most valuable.

  • Drive cross-team strategy: Contribute to team-wide priorities, including donor landscape analysis, partnership strategy with peer foundations and advisories, and material development.

What will set you up for success

The ideal candidate would have the experience and expertise necessary to serve as a Program Officer within one of our existing GCR teams, but with a preference to work in an external-facing, relationship-driven environment. Here are some traits we’re looking for:

  • Ability to clearly explain AI risk concepts: Has enough knowledge and insight to present core arguments and trade-offs to varied audiences; understands the landscape of AI interventions and can speak credibly about complex topics.

  • Pre-existing GCR network: Familiarity with the AI safety and biosecurity ecosystem; knows the key organizations, funders, and ideas.

  • Sociable: Draws energy from in-person relationship building; enjoys spending time in social settings like happy hours, conferences, and small group meetings.

  • High-stakes communicator: Comfortable with accomplished leaders; offers candid, decision-relevant advice.

  • Relationship builder with judgment: Tailors engagement; balances persistence with respect for constraints.

  • Operations mindset: Juggles multiple workflows; keeps systems clean; moves quickly without dropping details.

  • Ownership and initiative: Spots bottlenecks, proposes fixes, and drives to-dos with minimal oversight.

  • Calibration and humility: Updates views as evidence changes; seeks and incorporates feedback.

Preferred background

We want someone with experience operating at a high level, iterating quickly, and building relationships with senior stakeholders. We expect that the most competitive candidates will already be familiar with the AI safety and biosecurity ecosystem and cost-effective, high-impact giving. We’re particularly interested in talking to people with the following backgrounds, though there are many others that may be a good fit.

  • People who have done direct work in AI and adjacent areas — for example, employment at a think tank, policy advocacy organization, or AI company.

  • People who have experience in partnerships, philanthropy, or client-service environments.

  • People who have experience in management consulting or investment research.

  • People who have built and led small teams or a growing function, especially one with high levels of senior visibility.

Prior fundraising exposure is a plus, but not required.

We’re open to a range of seniority levels for this role, and we don’t want pay or title to be a blocker. Please consider applying even if you feel you have more or less experience than this description implies is necessary to do this job well.

Role details & benefits

  • Compensation: The baseline compensation for this role is $319,500, which would be distributed as a base salary of $295,000 and an unconditional 401(k) grant of $24,500.

    • These compensation figures assume a location in the San Francisco Bay Area. There would be a downward adjustment for candidates based elsewhere.

  • Location: San Francisco Bay Area strongly preferred

    • We will support candidates with the costs of relocation to the Bay.

    • We are happy to consider sponsoring U.S. work authorization. However, we don’t control who is and isn’t eligible for a visa and can’t guarantee visa approval.

    • Many of the Bay Area team work from the San Francisco office or out of a Berkeley coworking space most days; we envision a mix of in-office and remote work for this role.

  • Benefits: Our benefits package includes:

    • Excellent health insurance (we cover 100% of premiums within the U.S. for you and any eligible dependents) and an employer-funded Health Reimbursement Arrangement for certain other personal health expenses.

    • Dental, vision, and life insurance for you and your family.

    • Four weeks of PTO recommended per year.

    • Four months of fully paid family leave.

    • A generous and flexible expense policy — we encourage staff to expense the ergonomic equipment, software, and other services that they need to stay healthy and productive. This policy also includes a productivity benefit, which provides a set amount for staff to expense items that enhance their productivity.

    • A continual learning policy that encourages staff to spend time on professional development with related expenses covered.

    • Support for remote work — we’ll cover a remote workspace outside your home if you need one, or connect you with a Coefficient Giving coworking hub in your city. We currently have offices in San Francisco and Washington, D.C., and multiple staff working from several other cities in the U.S. and elsewhere.

    • We can’t always provide every benefit we offer U.S. staff to international hires, but we’re working on it (and will usually provide cash equivalents of any benefits we can’t offer in your country).

  • Start date: Ideally, we’d like new hires to start as soon as possible after receiving an offer, but we can be flexible for exceptional candidates.

We aim to employ people with many different experiences, perspectives, and backgrounds who share our passion for accomplishing as much good as we can. We are committed to creating an environment where all employees have the opportunity to succeed, and we do not discriminate based on race, religion, color, national origin, gender, sexual orientation, or any other legally protected status.

If you need assistance or an accommodation due to a disability, or have any other questions about applying, please contact jobs@coefficientgiving.org.

Please apply by 11:59 p.m. Pacific Time on April 5, 2026 to be considered.

U.S.-based Program staff are typically employed by Coefficient Giving LLC, which is not a 501(c)(3) tax-exempt organization. As such, this role is unlikely to be eligible for public service loan forgiveness programs.

We may use AI to assist in the initial screening of applications, including to detect whether candidates have used AI models in drafting their application. Decisions are always made by a human on our team. If you have any questions about our use of AI tools, you can email jobs@coefficientgiving.org.